Bolus) Short acting insulin is given pre-meals, intermediate or long acting before sleep (Basal).
Studies in both children and adults have shown that it is possible to improve glucose control with this regime if used correctly.
More information:
http://www.leedsth.nhs.uk/sites/diabetes/tips/MDI.php
http://www.leedsth.nhs.uk/sites/diabetes/insular/MultipleInsulin.php
http://www.leedsth.nhs.uk/sites/diabetes/information/Insulinmixturespg2.php